- Preheat the oven. Preheat your oven to 350°F (175°C) so it will be nice and hot by the time your meatloaf is ready to bake. 
- Beat the eggs. Break the eggs into a small bowl, then beat lightly with a fork, this makes them easier to mix in and more evenly distributed. 
- Mix the main ingredients. Place the ground beef into a large bowl along with the stuffing mix, minced onion, garlic powder, water, and ketchup. Mix well (with your hands or a spoon). 
- Add the eggs. Add the beaten eggs and fold gently until everything is just combined — don’t overmix or your meatloaf can be tough. 
- Shape and top with ketchup. Form the mixture into a loaf and transfer to a greased baking dish or loaf pan. Just smear some ketchup on top for that sweet and tangy glaze. 
- Bake and serve. Bake for 50–60 minutes, or until center registers 160°F. Allow it to rest for a few minutes, add a sprinkle of fresh parsley and serve up with some mashed potatoes or your favorite veggie side!